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Percutaneous ablation for adrenal metastasis from non-small-cell lung cancer: comparison between cryoablation and microwave ablation.
Zhang, Wei; Liu, Wei; Wu, Zheng-Long; Zhao, Zhi-Yong; Ma, Wei-Ming.
Affiliation
  • Zhang W; Department of Liver Disease, Daxing Hospital, Xi'an, China.
  • Liu W; Department of Oncology, Xuzhou Central Hospital, Xuzhou, China.
  • Wu ZL; Department of Radiology, Xuzhou Central Hospital, Xuzhou, China.
  • Zhao ZY; Department of Ultrasound, Shenzhen Hospital, Beijing University of Chinese Medicine, Shenzhen, China.
  • Ma WM; Department of Urological Surgery, Xuzhou Central Hospital, Xuzhou, China.
Wideochir Inne Tech Maloinwazyjne ; 19(1): 52-59, 2024 Mar.
Article in En | MEDLINE | ID: mdl-38974767
ABSTRACT

Introduction:

While cryoablation (CA) and microwave ablation (MWA) have both been implemented as approaches to the treatment of adrenal metastasis (AM), the outcomes associated with these two therapeutic strategies remain unclear.

Aim:

To compare the safety and efficacy of CA and MWA as treatments for AM in patients with non-small-cell lung cancer (NSCLC). Material and

methods:

Consecutive patients with AM secondary to NSCLC from January 2015 to December 2020 underwent CA or MWA. Treatment-related outcomes and complications were retrospectively compared between these groups.

Results:

In total, 68 NSCLC patients with isolated AM were enrolled in this study, of whom 35 and 33 underwent treatment with CA and MWA, respectively. Primary complete ablation rates in the CA and MWA groups were 91.4% (32/35) and 93.9% (31/33) respectively (p = 1.000), while a 100% secondary complete ablation rate was observed for both groups. Hypertensive crisis incidence affected 11.4% (4/35) and 9.1% (3/33) of patients in the CA and MWA groups (p = 1.000), respectively, while 8 (22.9%) and 8 (24.2%) patients in these corresponding groups experienced local progression after ablation that was detected during the follow-up period (p = 0.893). Patients in the CA and MWA groups exhibited a median progression-free survival of 18 and 22 months, respectively (p = 0.411), while the corresponding median overall survival of patients in these groups was 25 and 29 months (p = 0.786).

Conclusions:

CT-guided CA and MWA appear to exhibit similar safety and efficacy profiles when employed to treat isolated AM in NSCLC patients.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Wideochir Inne Tech Maloinwazyjne Year: 2024 Document type: Article Affiliation country: China Country of publication: Poland

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Wideochir Inne Tech Maloinwazyjne Year: 2024 Document type: Article Affiliation country: China Country of publication: Poland