Therapeutic Efficacy of Mirogabalin in managing Trigeminal Neuralgia.
J Clin Exp Dent
; 16(5): e652-e655, 2024 May.
Article
in En
| MEDLINE
| ID: mdl-38988761
ABSTRACT
Trigeminal neuralgia presents significant challenges in management, often requiring alternative pharmacotherapy due to resistance or side effects to first-line medications like carbamazepine. This case series investigates the efficacy and safety of mirogabalin, a novel α2δ ligand, in six trigeminal neuralgia patients. Mirogabalin demonstrated varying degrees of pain reduction, with an average Numerical Rating Scale improvement rate of 43.1%. Side effects were generally mild, with drowsiness and dizziness being the most common. Despite limited efficacy in some cases, mirogabalin shows promise as a potential treatment option for trigeminal neuralgia, warranting further investigation. Key wordsTrigeminal neuralgia, mirogabalin, α2δ lig.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
J Clin Exp Dent
Year:
2024
Document type:
Article
Affiliation country:
Japan