CF<sub>2</sub>H: a fascinating group for application in drug development enabling modulation of many molecular properties. | Future Med Chem;16(12): 1181-1184, 2024. | MEDLINE

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CF₂H: a fascinating group for application in drug development enabling modulation of many molecular properties.

Saphier, Sigal; Zafrani, Yossi.

Affiliation

Saphier S; The Department of Organic Chemistry, Israel Institute for Biological Research, Ness-Ziona, 74100, Israel.
Zafrani Y; The Department of Organic Chemistry, Israel Institute for Biological Research, Ness-Ziona, 74100, Israel.

Future Med Chem ; 16(12): 1181-1184, 2024.

Article in En | MEDLINE | ID: mdl-38989984

Key words

acidity; basicity; difluoromethyl; hydrogen bond; lipophilicity; polarity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Future Med Chem Year: 2024 Document type: Article Affiliation country: Israel Country of publication: United kingdom

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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Future Med Chem Year: 2024 Document type: Article Affiliation country: Israel Country of publication: United kingdom