NON-SELECTIVE BETA-BLOCKERS IN CIRRHOTIC PATIENTS WITH REFRACTORY ASCITES: WHERE ARE WE?
Arq Gastroenterol
; 61: e23157, 2024.
Article
in En
| MEDLINE
| ID: mdl-39046001
ABSTRACT
BACKGROUND:
The established use of non-selective beta-blockers (NSBB) in the primary and secondary prevention of esophageal varices has recently been questioned in the subgroup of patients with diuretic-refractory ascites.OBJECTIVE:
Critically analyze the body of evidence on the topic in order to assist clinical decisions.METHODS:
A literature review was carried out in the Pubmed® and Scielo® databases. In total, 20 articles between 2010 and 2023 were read by independent researchers.CONCLUSION:
It remains doubtful whether the use of NSBB is deleterious in cirrhotic patients with refractory ascites, however our literature review allows us to conclude that these drugs should not be proscribed in these patients. On the contrary, a doctor-patient decision based on tolerability and hemodynamic parameters certainly seems to be a safe conduct.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Ascites
/
Esophageal and Gastric Varices
/
Adrenergic beta-Antagonists
/
Liver Cirrhosis
Limits:
Humans
Language:
En
Journal:
Arq Gastroenterol
Year:
2024
Document type:
Article
Affiliation country:
Brazil
Country of publication:
Brazil