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Restaging magnetic resonance imaging of the rectum after neoadjuvant therapy: a practical guide.
Horvat, Natally; Miranda, João; Kinochita, Fernanda; de Carvalho, Tiago Lins; Torri, Giovanni Brondani; Lopes, Thiago José Pinheiro; Nomura, Cesar Higa.
Affiliation
  • Horvat N; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Miranda J; Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, SP, Brazil.
  • Kinochita F; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • de Carvalho TL; Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, SP, Brazil.
  • Torri GB; Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, SP, Brazil.
  • Lopes TJP; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Nomura CH; Department of Radiology and Diagnostic Imaging, Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil.
Radiol Bras ; 57: e20240004, 2024.
Article in En | MEDLINE | ID: mdl-39050261
ABSTRACT
Colorectal cancer is the third most common cancer and the second leading cause of cancer-related death. Rectal cancer accounts for approximately one-third of new colorectal cancer cases, with adenocarcinoma as the predominant subtype. Despite an overall decline in colorectal cancer incidence and mortality, due to advancements in screening, early diagnosis, and treatment options, there is a concerning increase in incidence rates among young patients. Recent significant advances in managing locally advanced rectal cancer, such as the establishment of different surgical approaches, neoadjuvant treatment using different protocols for high-risk cases, and the adoption of organ-preservation strategies, have increased the importance of the role played by radiologists in locoregional assessment on magnetic resonance imaging at baseline, at restaging, and during active surveillance of patients with rectal cancer. In this article, we review the role of restaging rectal magnetic resonance imaging after neoadjuvant therapy, providing radiologists with a practical, step-by-step guide for assessing treatment response.
RESUMO
O câncer colorretal é o terceiro câncer mais comum e a segunda principal causa de morte relacionada ao câncer. O câncer retal representa aproximadamente um terço dos novos casos de câncer colorretal, sendo o adenocarcinoma o subtipo predominante. Apesar de uma diminuição geral na incidência e mortalidade, impulsionada por avanços na prevenção do câncer, diagnóstico precoce e opções de tratamento aprimoradas, há uma preocupante elevação nas taxas entre os pacientes jovens. Avanços recentes significativos no manejo do câncer retal localmente avançado, como abordagens cirúrgicas, o uso de diferentes protocolos de tratamento neoadjuvante para casos de alto risco e a adoção de estratégias de preservação de órgãos, aumentaram o papel dos radiologistas na avaliação locorregional por meio da ressonância magnética na avaliação inicial, reestadiamento e vigilância ativa de pacientes com câncer retal. Este manuscrito tem como objetivo revisar o papel da ressonância magnética retal no reestadiamento após terapia neoadjuvante, fornecendo aos radiologistas um guia prático para revisar exames nesse contexto.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Radiol Bras Year: 2024 Document type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Radiol Bras Year: 2024 Document type: Article Affiliation country: United States