A case of a lidocaine intoxication of a 12 week old boy due to a circumcision in a domestic setting - clinical, toxicological and forensic aspects.
Forensic Sci Med Pathol
; 2024 Aug 01.
Article
in En
| MEDLINE
| ID: mdl-39088142
ABSTRACT
Lidocaine is a local anaesthetic commonly used during circumcision for dorsal penile nerve block (DPNB). We describe a case of a 12-week-old infant who presented generalized seizures due to local anesthetic systemic toxicity after Lidocaine administration for circumcision in a non-hospital setting. Serum concentrations of Lidocaine (16.4 mg/L) and its main active metabolite monoethylglycinexylidide (MEGX, 1.36 mg/L) were determined by HPLC-DAD, in a sample collected shortly after administration, which were higher than in comparable cases reported in literature. The reason for the overdose was assumed to be accidental systemic application. Due to suspicion of an improperly performed circumcision and bodily harm, police was involved and a clinical forensic examination was carried out. Here, we present analytical, clinical and forensic aspects of this case.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Forensic Sci Med Pathol
Journal subject:
JURISPRUDENCIA
/
MEDICINA
/
PATOLOGIA
Year:
2024
Document type:
Article
Affiliation country:
Germany