Near-Infrared Fluorescent Probe for the Detection of Cysteine.
Appl Spectrosc
; 78(7): 744-752, 2024 Jul.
Article
in En
| MEDLINE
| ID: mdl-39096170
ABSTRACT
Hemicyanine dyes are an ideal structure for building near-infrared fluorescent probes due to their excellent emission wavelength properties and biocompatibility in biological imaging field. Developing a near-infrared fluorescent probe capable of detecting cysteine (Cys) was the aim of this study. A novel developed fluorescent probe P showed high selectivity and sensitivity to Cys in the presence of various analytes. The detection limit of P was found to be 0.329â
µM. The MTT assay showed that the probe was essentially non-cytotoxic. Furthermore, the probe was successfully used as cysteine imaging in living cells and mice.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cysteine
/
Fluorescent Dyes
Limits:
Animals
/
Humans
Language:
En
Journal:
Appl Spectrosc
Year:
2024
Document type:
Article
Affiliation country:
China
Country of publication:
United States