Camera-based near-infrared autofluorescence versus visual identification in total thyroidectomy for parathyroid function preservation: Systematic review and meta-analysis of randomized clinical trials.
Head Neck
; 2024 Aug 05.
Article
in En
| MEDLINE
| ID: mdl-39104194
ABSTRACT
BACKGROUND:
Hypocalcemia is the most common postoperative complication of total thyroidectomy. Near-infrared autofluorescence (NIRAF) technology is a surgical adjunct that has been increasingly utilized with the aim of preventing postoperative hypocalcemia, but its clinical benefits have not yet been firmly established. The aim of this study was to assess the clinical benefit of utilizing NIRAF technology in patients undergoing total thyroidectomy.METHODS:
A systematic review and meta-analysis of randomized clinical trials was performed according to PRISMA guidelines.RESULTS:
Seven randomized clinical trials with 1437 patients (318 males, 22.13%) undergoing total thyroidectomy were included for analysis. Risk of postoperative hypocalcemia was reduced in the NIRAF arm (RR, 0.65; 95%CI, 0.50-0.84). Use of NIRAF was also associated with a reduction in the risk of permanent parathyroid dysfunction (RR, 0.46; 95%CI, 0.22-0.95) and inadvertent parathyroid gland resection (RR, 0.40; 95%CI, 0.26-0.60).CONCLUSIONS:
We present a systematic review and meta-analysis of randomized clinical trials examining the impact of NIRAF technology on preservation of parathyroid function. Our results suggest that use of camera-based NIRAF technology reduces the risk of postoperative hypocalcemia, permanent parathyroid dysfunction, and inadvertent parathyroid gland resection.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Head & neck
/
Head Neck
/
Head neck
Journal subject:
NEOPLASIAS
Year:
2024
Document type:
Article
Affiliation country:
United States
Country of publication:
United States