Deliberation concerning the role of M1-type macrophage subset in oral carcinogenesis.
J Exp Clin Cancer Res
; 43(1): 220, 2024 Aug 08.
Article
in En
| MEDLINE
| ID: mdl-39113068
ABSTRACT
Over the last decade, accumulating evidence has suggested that tumor-associated macrophages (TAMs) play a significant role in the tumor development. This commentary wishes to highlight the findings by You, et al. that M1-like TAMs could cascade a mesenchymal/stem-like phenotype of oral squamous cell carcinoma (OSCC) via the IL6/Stat3/THBS1 feedback loop. These unprecedented findings identified M1-like TAMs-regulated processes as potentially tumor-promotion in the context of OSCC immunomicroenvironment.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Mouth Neoplasms
/
Macrophages
Limits:
Animals
/
Humans
Language:
En
Journal:
J Exp Clin Cancer Res
Year:
2024
Document type:
Article
Affiliation country:
China
Country of publication:
United kingdom