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Risk of gastrointestinal bleeding in Asian patients receiving oral anticoagulants for stroke prevention in atrial fibrillation.
Diaz, Alejandro Bimbo; Chow, Jeremy; Hoo, Fan Kee; Keong, Gary Lee Chin; Venketasubramanian, Narayanaswamy; Rey, Nannette; Rogelio, Gregorio; Mehta, Radhika.
Affiliation
  • Diaz AB; University of Santo Tomas Hospital, Manila, Philippines.
  • Chow J; Asian Heart & Vascular Centre, Singapore, Singapore.
  • Hoo FK; University Putra Malaysia, Serdang, Malaysia.
  • Keong GLC; Thomson Hospital Kota Damansara, Petaling Jaya, Malaysia.
  • Venketasubramanian N; Raffles Hospital, Singapore, Singapore.
  • Rey N; de La Salle Medical and Health Sciences Institute, Dasmarinas Cavite, Philippines.
  • Rogelio G; St Luke's Medical Center, Quezon City, Philippines.
  • Mehta R; Menarini Asia-Pacific Pte Ltd, Singapore, Singapore.
Drugs Context ; 132024.
Article in En | MEDLINE | ID: mdl-39165614
ABSTRACT
Non-vitamin K antagonist oral anticoagulants (NOACs) are increasingly used for stroke prevention in atrial fibrillation. At the Asia Pacific Advancing Patient care with EdoXaban 2023 meeting, experts shared insights on gastrointestinal bleeding with NOACs for stroke prevention in atrial fibrillation in Asian clinical practice, where NOACs have gained widespread acceptance due to their favourable profiles. Gastrointestinal bleeding risk varies amongst NOACs, emphasizing the importance of diligent patient assessment, dosage selection and vigilant monitoring. Edoxaban emerged as a viable option with a low gastrointestinal bleeding risk profile in Asian compared with non-Asian patients, supporting its continued clinical utilization for appropriate patients.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Drugs Context Year: 2024 Document type: Article Affiliation country: Philippines Country of publication: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Drugs Context Year: 2024 Document type: Article Affiliation country: Philippines Country of publication: United kingdom