Exploration of the Muribaculaceae Family in the Gut Microbiota: Diversity, Metabolism, and Function.
Nutrients
; 16(16)2024 Aug 12.
Article
in En
| MEDLINE
| ID: mdl-39203797
ABSTRACT
The gut microbiota are mainly composed of Bacteroidetes and Firmicutes and are crucial for metabolism and immunity. Muribaculaceae are a family of bacteria within the order Bacteroidetes. Muribaculaceae produce short-chain fatty acids via endogenous (mucin glycans) and exogenous polysaccharides (dietary fibres). The family exhibits a cross-feeding relationship with probiotics, such as Bifidobacterium and Lactobacillus. The alleviating effects of a plant-based diet on inflammatory bowel disease, obesity, and type 2 diabetes are associated with an increased abundance of Muribaculaceae, a potential probiotic bacterial family. This study reviews the current findings related to Muribaculaceae and systematically introduces their diversity, metabolism, and function. Additionally, the mechanisms of Muribaculaceae in the alleviation of chronic diseases and the limitations in this field of research are introduced.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Probiotics
/
Bacteroidetes
/
Gastrointestinal Microbiome
Limits:
Animals
/
Humans
Language:
En
Journal:
Nutrients
Year:
2024
Document type:
Article
Affiliation country:
China
Country of publication:
Switzerland