Vision loss and diabetic retinopathy prevalence and risk among a cohort of Indigenous and non-Indigenous Australians with type 2 diabetes receiving renal haemodialysis treatment: The retinopathy in people currently on renal dialysis (RiPCORD) study.
Prim Care Diabetes
; 18(5): 547-554, 2024 Oct.
Article
in En
| MEDLINE
| ID: mdl-39232978
ABSTRACT
AIMS:
Diabetic nephropathy, vision loss and diabetic retinopathy (DR) are frequent comorbidities among individuals with type 2 diabetes (T2D). The Retinopathy in People Currently On Renal Dialysis (RiPCORD) study sought to examine the epidemiology and risk of vision impairment (VI) and DR among a cohort of Indigenous and non-Indigenous Australians with T2D currently receiving haemodialysis for end-stage renal failure (ESRF).METHODS:
A total of 106 Indigenous and 109 non-Indigenous Australians were recruited in RiPCORD across five haemodialysis centres in urban and remote settings. Clinical assessments, questionnaires and medical record data determined the rates of ocular complications and risk factor profiles.RESULTS:
Prevalence rates include unilateral VI, 23.5â¯%; bilateral VI, 11.7â¯%; unilateral blindness, 14.2â¯%; and bilateral blindness, 3.7â¯%, with no significant differences between sub-cohorts (p=0.30). DR prevalence rates were 78.0â¯% among non-Indigenous Australians and 93.1â¯% among Indigenous Australians (p=<0.001). Non-Indigenous ethnicity (OR 0.28) and pre-dialysis diastolic blood pressure (OR 0.84 per 10-mmHg) were protective, while peripheral vascular disease (OR 2.79) increased DR risk.CONCLUSIONS:
Ocular complications among individuals with T2D and ESRF are disproportionately high, especially for Indigenous Australians, and beyond what can be accounted for by risk factor variation. Findings suggest a need to improve screening and preventative efforts within this high-risk population group.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Renal Dialysis
/
Diabetes Mellitus, Type 2
/
Diabetic Nephropathies
/
Diabetic Retinopathy
/
Kidney Failure, Chronic
Country/Region as subject:
Oceania
Language:
En
Journal:
Prim Care Diabetes
Journal subject:
ENDOCRINOLOGIA
Year:
2024
Document type:
Article
Country of publication:
United kingdom