[Embryonal malformation following etretinate therapy of Darier's disease in the mother]. / Embryonale Fehlbildung bei Etretinat-Therapie der Mutter wegen Morbus Darier.
Dtsch Med Wochenschr
; 111(2): 60-2, 1986 Jan 10.
Article
in De
| MEDLINE
| ID: mdl-3940838
A 22-year-old woman suffering from dyskeratosis follicularis Darier became pregnant 4 months after the last dose of etretinate (Tigason). The pregnancy was terminated in the 10th week because of teratogenic risk. The pathological examination of the fetus revealed severe malformation of the left leg with aplasia of tibia and fibula, as well as hypoplasia of the left femur. This observation emphasises the necessity of effective contraception even after discontinuation of etretinate therapy.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pregnancy Complications
/
Abnormalities, Drug-Induced
/
Abnormalities, Multiple
/
Etretinate
/
Darier Disease
Limits:
Adult
/
Female
/
Humans
/
Pregnancy
Language:
De
Journal:
Dtsch Med Wochenschr
Year:
1986
Document type:
Article
Country of publication:
Germany