[Relation between glycohemoglobin, hypoxia parameters and diabetic microangiopathy]. / Untersuchungen zum Zusammenhang zwischen Glykohämoglobin, Hypoxieparametern und diabetischer Mikroangiopathie.

ABSTRACT

In normal persons and in diabetics with and without tissue injuries was tried to find out a connection between the glycolyzed haemoglobin and the parameters of hypoxia. In a small number of cases no clearly evident correlation between the concentrations of the 2,3-diphosphoglycerate and the lactate to the glycohaemoglobins was found. In connection with this investigation pathobiochemical considerations of late diabetic injuries are carried out, which are the consequence of inconveniences in the usability of glucose of diabetics and the connected with this non-enzymatic glycosylation of various proteins.