Serum progesterone in nonpregnant women. I. Comparative study of serum progesterone concentration and urinary pregnanediol excretion.

ABSTRACT

PIP The normal range of serum progesterone (measured by radioimmunoassay) and urinary pregnanediol during the menstrual cycle was determined in 86 patients (33 control and 53 with menstrual disorders or sterility) and the values were found to show a logarithmic distribution. The overall correlation between serum progesterone and urinary pregnanediol concentration was .82. Clinical diagnostic applications of these measurements include 1) anovulatory demonstration, 2) determination of secondary amenorrhea, 3) investigation of prolonged cycles, 4) investigation of probable luteal insufficiency, and 5) response to clomiphene citrate.^ieng