Biochemical assessment of thiamine nutrition in childhood.
Eur J Pediatr
; 131(4): 229-35, 1979 Aug.
Article
in En
| MEDLINE
| ID: mdl-477681
ABSTRACT
The activity of red cell transketolase and TPP-effect were determined in 1028 infants and children, aged 1 month to 14 years, using a micromethod. All the children were healthy and without evidence of malnutrition. Transketolase activity decreased in the second year of life, followed by a constant increase up to the 6th year. Activity did not change in the next four years, then a steady decrease occurred. TPP-effect was not as stable as transketolase activity, and decreased significantly from years 3 to 5 and increased significantly from years 5 to 7. Beginning with year 10, TPP-effect decreased gradually. 6.6% of all children investigated had marginally deficient TPP-effects and 1.3% were biochemically deficient without clinical signs of avitaminosis. A group of 37 adults had transketolase activities and TPP-effect comparable to those of the 13 year-olds. Effect appeared to be marginal in 5.4% and deficient in 2.7%.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Thiamine
/
Nutritional Physiological Phenomena
Type of study:
Diagnostic_studies
Limits:
Adolescent
/
Child
/
Child, preschool
/
Humans
/
Infant
Language:
En
Journal:
Eur J Pediatr
Year:
1979
Document type:
Article