Role of operative trauma: explosive metastases of similar size following amputation of the primary leg tumor.
Tumori
; 65(5): 527-38, 1979 Oct 31.
Article
in En
| MEDLINE
| ID: mdl-516175
ABSTRACT
Trauma produced by amputation of a limb bearing the primary tumor influenced pulmonary metastases of the Carcinosarcoma of Walker 256 of the rat. This enhancement was present in 38% of the animals following the removal of a limb bearing the primary tumor; and in 29% of those in which the controlateral limb without tumor was amputated. A significant prolongation of the clotting time, an elevation of fibrinogen factor II and VII and a rapid consumption of factor VIII present soon after trauma may have been the parameter responsible for the increase of pulmonary metastases seen in this study.
Search on Google
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Postoperative Complications
/
Carcinoma 256, Walker
/
Lung Neoplasms
/
Neoplastic Cells, Circulating
/
Neoplasm Seeding
Limits:
Animals
Language:
En
Journal:
Tumori
Year:
1979
Document type:
Article