[Dipole cooperative model of ion channels in excitable biomembranes. I. Gating currents]. / Dipol'naia kooperativnaia model' ionnykh kanalov vozbusimykh biomembran. I. Vorotnye toki.

ABSTRACT

The experimental data on gating currents are analyzed in terms of dipole cooperative model of ionic channel. The dependence of displaced charge on potential is calculated. A comparison between the theory and experiment allows to establish the cooperative part of the charged gating subunits energy. It is shown that kinetics of gating particles displacement is nearly exponential. The theoretical dependence of characteristic times on the potential during testing pulse of voltage agrees qualitatively with the experimental curves.