[Immunosuppressive effect of a human serum ferroprotein of hepatic origin: alpha-2-HF-globulin]. / Effet immunosuppresseur d'une ferroprotéine sérique humaine d'origine hépatique l'alpha 2 HF-globuline. Action sur la synthèse des anticorps in vitro

alpha 2HF, a serum ferroprotein increased during some malignant diseases, displays a suppressive effect on in vitro antibody responses, whether T-independent or T-dependent. This effect is not related to the presence of iron, nor to the macroglobulin nature of the molecule. The immunosuppressive properties of alpha 2 HF might depend on its carbohydrate moeity.