Identity of the neoplastic alkaline phosphatase as revealed with monoclonal antibodies to the placental form of the enzyme.
Am J Clin Pathol
; 82(2): 173-7, 1984 Aug.
Article
in En
| MEDLINE
| ID: mdl-6380267
ABSTRACT
A panel of six monoclonal antibodies and a conventional polyclonal antibody raised against human placental alkaline phosphatase (ALP) were used to characterize the alkaline phosphatase detected by means of histochemistry on tumors of breast, ovary, lung, gastrointestinal tract, and kidney. Complete antigenic identity between the tumor ALP and the placental ALP was found only in one lung tumor. However, ten tumors reacted with the polyclonal antibody and some monoclonal antibodies, thus exhibiting partial identity with the placental ALP.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Placenta
/
Alkaline Phosphatase
/
Antibodies, Monoclonal
/
Antigens, Neoplasm
Limits:
Animals
/
Humans
Language:
En
Journal:
Am J Clin Pathol
Year:
1984
Document type:
Article
Country of publication:
ENGLAND
/
ESCOCIA
/
GB
/
GREAT BRITAIN
/
INGLATERRA
/
REINO UNIDO
/
SCOTLAND
/
UK
/
UNITED KINGDOM