The value of immunohistochemical markers in the diagnosis of cervical neoplasia.
Br J Obstet Gynaecol
; 91(10): 1037-41, 1984 Oct.
Article
in En
| MEDLINE
| ID: mdl-6386038
ABSTRACT
This study was designed to determine whether immunohistochemical stains for tumour-associated markers may be useful in the detection and differential diagnosis of premalignant and malignant lesions of the cervix. The expression of four markers detected by monoclonal antibodies, human milk fat globule 1 and 2 (HMFG-1 and 2), Ca1 and anti-carcinoembryonic antigen (anti-CEA) on conventional histological sections of various cervical lesions has been investigated. None of these markers was specific for neoplastic lesions of the cervix and all four markers were expressed by metaplastic as well as neoplastic cells, and it was concluded that their application in the histopathological examination of the cervix is limited.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Uterine Cervical Neoplasms
Type of study:
Diagnostic_studies
Limits:
Female
/
Humans
Language:
En
Journal:
Br J Obstet Gynaecol
Year:
1984
Document type:
Article