[Protein binding of steroids]. / Les liaisons protéiniques des stéroïdes.

ABSTRACT

The role of protein-binding in the physiology of steroids is of great complexity. The following are envisaged the types of protein, methods of binding and the affinity of steroids for proteins, and the variations in free fraction according to plasma protein levels; the functions of binding proteins on the activity and clearance of steroids as well as on the peripheral conversion of androgens; the factors which influence variations in binding protein levels and in particular the influence of circulating levels of natural hormones and the influence of hormone treatment.