J segment in human delta chains.

ABSTRACT

We report the complete sequence of a cyanogen bromide fragment of a human delta chain (ErI). Its interest lies in the fact that it contains the peptide joining the V delta to the C delta 1 region. The presented sequence is compared with the homologous region of other human heavy chain classes and subclasses. The possibility that human delta chains and other human heavy chains have in their chromosomal DNA a short J sequence, is discussed.