Pituitary-thyroid axis after bilateral orchiectomy in men.

Valenti, G; Banchini, A; Zavaroni, D; Vescovi, P P; Ponticelli, P; Hafez, E S

Valenti, G; Banchini, A; Zavaroni, D; Vescovi, P P; Ponticelli, P; Hafez, E S.

Arch Androl ; 9(2): 171-4, 1982 Sep.

Article in En | MEDLINE | ID: mdl-6816159

ABSTRACT

ABSTRACT

The functional interaction between the testis and thyroid was evaluated in 13 patients affected by prostatic carcinoma before and after bilateral orchiectomy. Two different patterns of thyroid hormones were noted. Immediately after surgery, free thyroxine (T4) increased and total triiodothyronine (T3) decreased probably as a result of surgical stress at anesthesia. Later, free T4 levels decreased while total T4 and thyroxine binding globulin (TBG) were unchanged. Such changes may be due to qualitative changes in binding proteins.

Subject(s)

Castration; Pituitary Gland/physiology; Thyroid Gland/physiology; Aged; Humans; Kinetics; Male; Middle Aged; Prostatic Neoplasms/surgery; Thyrotropin/blood; Thyrotropin-Releasing Hormone; Thyroxine/blood; Thyroxine-Binding Proteins/metabolism; Triiodothyronine/blood

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Collection: 01-internacional Database: MEDLINE Main subject: Pituitary Gland / Thyroid Gland / Castration Type of study: Qualitative_research Limits: Aged / Humans / Male / Middle aged Language: En Journal: Arch Androl Year: 1982 Document type: Article

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