Blood flow in human tumors during hyperthermia therapy: demonstration of vasoregulation and an applicable physiological model.
J Surg Oncol
; 23(2): 125-32, 1983 Jun.
Article
in En
| MEDLINE
| ID: mdl-6855242
A quantitative assessment of the effect of localized magnetic-loop hyperthermia on blood flow was performed in 12 human tumors using the 133Xe clearance method. Because blood flow in these tumors changed in response to needle injection, a physiologically based, one-compartment model was developed that included both a hyperemic and a steady-state component. In six tumors, changes in blood flow induced by heat were also observed. The ability of tumor vessels to respond dynamically to stress and the degree of response may be predictive of tumor heating capacity and subsequent therapeutic response.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Sarcoma
/
Hot Temperature
/
Abdominal Neoplasms
/
Melanoma
Type of study:
Prognostic_studies
Limits:
Humans
Language:
En
Journal:
J Surg Oncol
Year:
1983
Document type:
Article
Country of publication:
United States