Multiclinic evaluation of the antihypertensive effect of a methyldopa, hydrochlorothiazine, and amiloride combination.
Clin Ther
; 3(3): 168-75, 1980.
Article
in En
| MEDLINE
| ID: mdl-7006811
ABSTRACT
A multiclinic, double-blind, randomized study in 361 patients with essential hypertension compared Aldoretic, (Merck & Co., Inc., New Jersey), a combination of methyldopa, hydrochlorothiazide, and amiloride with the combination of hydrochlorothiazide and amiloride and with methyldopa alone. At the end of week 12, the proportion of patients who were classified as normotensive (diastolic less than or equal to 90 mm Hg) was 61% in the group treated with Aldoretic, which was statistically significantly greater than the 48% in the hydrochlorothiazide/amiloride group and the 35% in the methyldopa group.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pyrazines
/
Amiloride
/
Hydrochlorothiazide
/
Hypertension
/
Methyldopa
Type of study:
Clinical_trials
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Clin Ther
Year:
1980
Document type:
Article