Isoxicam and related 4-hydroxy-N-isoxazolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxides. Potent nonsteroidal antiinflammatory agents.

Zinnes, H; Sircar, J C; Lindo, N; Schwartz, M L; Fabian, A C; Shavel, J; Kasulanis, C F; Genzer, J D; Lutomski, C; DiPasquale, G

Zinnes, H; Sircar, J C; Lindo, N; Schwartz, M L; Fabian, A C; Shavel, J; Kasulanis, C F; Genzer, J D; Lutomski, C; DiPasquale, G.

J Med Chem ; 25(1): 12-8, 1982 Jan.

Article in En | MEDLINE | ID: mdl-7086815

Subject(s)

Anti-Inflammatory Agents/pharmacology; Isoxazoles/pharmacology; Oxazoles/pharmacology; Piroxicam/analogs & derivatives; Thiazines/pharmacology; Animals; Anti-Inflammatory Agents/chemical synthesis; Isoxazoles/chemical synthesis; Male; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Thiazines/chemical synthesis

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Collection: 01-internacional Database: MEDLINE Main subject: Oxazoles / Thiazines / Piroxicam / Isoxazoles / Anti-Inflammatory Agents Limits: Animals Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 1982 Document type: Article Country of publication: United States

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