Lysophosphatidylserine-induced release of intra-cellular amines in mice.
Br J Pharmacol
; 69(1): 11-2, 1980 May.
Article
in En
| MEDLINE
| ID: mdl-7378649
ABSTRACT
In the presence of mouse plasma, lysophosphatidylserine stimulates histamine secretion from isolated mast cells. The extensive modification of carbohydrate metabolism produced by lysophosphatidylserine in mice was largely prevented by the antihistaminic drug, pyrilamine. However, to prevent completely the change in carbohydrate metabolism induced by lysophosphatidylserine the administration of an antihistamine and an adrenoceptor antagonist was required. It is concluded that the effect of lysophosphatidylserine in mice is due to release of intracellular amines. Histamine and catecholamines are involved.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Phosphatidylserines
/
Biogenic Amines
/
Lysophospholipids
Limits:
Animals
Language:
En
Journal:
Br J Pharmacol
Year:
1980
Document type:
Article