Renal accumulation of amikacin, tobramycin and gentamycin in the rat.
Experientia
; 34(10): 1335-6, 1978 Oct 15.
Article
in En
| MEDLINE
| ID: mdl-738411
ABSTRACT
Free and total concentrations of amikacin, tobramycin and gentamycin were measured separately in the rat kidney after equal weight by weight doses. The accumulation of aminoglycosides followed the order amikacin less than tobramycin less than gentamycin. The ratio between free and total aminoglycosides was similar (about 0.6) in all 3 aminoglycosides and independent on the length of administration.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Tobramycin
/
Amikacin
/
Gentamicins
/
Kanamycin
/
Kidney
/
Anti-Bacterial Agents
Limits:
Animals
Language:
En
Journal:
Experientia
Year:
1978
Document type:
Article