Synthetic mimics of juxtaposed amino- and carboxyl-terminal peptide domains of human gamma interferon block ligand binding to human gamma interferon receptor.

Seelig, G F; Prosise, W W; Taremi, S S

Seelig, G F; Prosise, W W; Taremi, S S.

Affiliation

Seelig GF; Schering-Plough Research Institute, Kenilworth, New Jersey 07033-0539.

J Biol Chem ; 269(1): 358-63, 1994 Jan 07.

Article in En | MEDLINE | ID: mdl-7506256

Subject(s)

Interferon-gamma/metabolism; Peptide Fragments/metabolism; Receptors, Interferon/metabolism; Amino Acid Sequence; Animals; Antibodies/immunology; Antibodies, Monoclonal/immunology; Epitopes; Humans; Interferon-gamma/chemistry; Interferon-gamma/immunology; Ligands; Mice; Molecular Sequence Data; Peptide Fragments/chemical synthesis; Rabbits; Receptors, Interferon/antagonists & inhibitors; Interferon gamma Receptor

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Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Interferon-gamma / Receptors, Interferon Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 1994 Document type: Article Country of publication: United States

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