Structural analysis of the deoxycytidine kinase gene in patients with acute myeloid leukemia and resistance to cytosine arabinoside.

Flasshove, M; Strumberg, D; Ayscue, L; Mitchell, B S; Tirier, C; Heit, W; Seeber, S; Schütte, J

Flasshove, M; Strumberg, D; Ayscue, L; Mitchell, B S; Tirier, C; Heit, W; Seeber, S; Schütte, J.

Affiliation

Flasshove M; Innere Klinik und Poliklinik (Tumorforschung) Universitätsklinikum Essen, Westdeutsches Tumorzentrum Essen, Germany.

Leukemia ; 8(5): 780-5, 1994 May.

Article in En | MEDLINE | ID: mdl-7514246

Subject(s)

Cytarabine/therapeutic use; Deoxycytidine Kinase/genetics; Leukemia, Myeloid, Acute/genetics; Adult; Aged; Base Sequence; Blotting, Southern; Codon; DNA Mutational Analysis; Deoxycytidine Kinase/metabolism; Drug Resistance/genetics; Female; Humans; Leukemia, Myeloid, Acute/drug therapy; Leukemia, Myeloid, Acute/enzymology; Male; Middle Aged; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; RNA, Neoplasm/analysis; RNA-Directed DNA Polymerase

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Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Cytarabine / Deoxycytidine Kinase Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 1994 Document type: Article Affiliation country: Germany Country of publication: United kingdom

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