Cyclic RGD peptide inhibits alpha 4 beta 1 interaction with connecting segment 1 and vascular cell adhesion molecule.

Cardarelli, P M; Cobb, R R; Nowlin, D M; Scholz, W; Gorcsan, F; Moscinski, M; Yasuhara, M; Chiang, S L; Lobl, T J

Cardarelli, P M; Cobb, R R; Nowlin, D M; Scholz, W; Gorcsan, F; Moscinski, M; Yasuhara, M; Chiang, S L; Lobl, T J.

Affiliation

Cardarelli PM; Tanabe Research Laboratories, San Diego, California 92121.

J Biol Chem ; 269(28): 18668-73, 1994 Jul 15.

Article in En | MEDLINE | ID: mdl-7518441

Subject(s)

Cell Adhesion Molecules/physiology; Cell Adhesion/drug effects; Fibronectins/metabolism; Integrins/physiology; Peptide Fragments/metabolism; Peptides, Cyclic/pharmacology; Amino Acid Sequence; Antibodies/pharmacology; Cell Adhesion Molecules/drug effects; Cell Line; Chromatography, Affinity; Dose-Response Relationship, Drug; Extracellular Matrix Proteins/metabolism; Fibronectins/antagonists & inhibitors; Humans; Integrin alpha4beta1; Integrins/antagonists & inhibitors; Kinetics; Molecular Sequence Data; Multigene Family; Peptide Fragments/antagonists & inhibitors; Peptides/chemical synthesis; Peptides/pharmacology; Recombinant Proteins/drug effects; Recombinant Proteins/metabolism; Structure-Activity Relationship; Transfection; Tumor Cells, Cultured; Vascular Cell Adhesion Molecule-1

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Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Peptides, Cyclic / Cell Adhesion Molecules / Integrins / Cell Adhesion / Fibronectins Limits: Humans Language: En Journal: J Biol Chem Year: 1994 Document type: Article

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