Guiding the selection of human antibodies from phage display repertoires to a single epitope of an antigen.

Jespers, L S; Roberts, A; Mahler, S M; Winter, G; Hoogenboom, H R

Jespers, L S; Roberts, A; Mahler, S M; Winter, G; Hoogenboom, H R.

Affiliation

Jespers LS; MRC Centre for Protein Engineering, MRC Centre, Cambridge, U.K.

Biotechnology (N Y) ; 12(9): 899-903, 1994 Sep.

Article in En | MEDLINE | ID: mdl-7521646

Subject(s)

Antibodies, Monoclonal/biosynthesis; Cloning, Molecular/methods; Epitopes/immunology; Genes, Immunoglobulin; Immunoglobulin Variable Region/biosynthesis; Immunoglobulin kappa-Chains/biosynthesis; Tumor Necrosis Factor-alpha/immunology; Amino Acid Sequence; Animals; Antigen-Antibody Reactions; Antigens/immunology; Base Sequence; DNA Primers; Glycosylation; Humans; Kinetics; Mice/immunology; Models, Structural; Molecular Sequence Data

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Collection: 01-internacional Database: MEDLINE Main subject: Immunoglobulin Variable Region / Genes, Immunoglobulin / Tumor Necrosis Factor-alpha / Cloning, Molecular / Immunoglobulin kappa-Chains / Antibodies, Monoclonal / Epitopes Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Biotechnology (N Y) Year: 1994 Document type: Article Affiliation country: United kingdom Country of publication: United States

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