Isolation and characterization of a highly attenuated respiratory syncytial virus (RSV) vaccine candidate by mutagenesis of the incompletely attenuated RSV A2 ts-1 NG-1 mutant virus.

Hsu, K H; Crowe, J E; Lubeck, M D; Davis, A R; Hung, P P; Chanock, R M; Murphy, B R

Hsu, K H; Crowe, J E; Lubeck, M D; Davis, A R; Hung, P P; Chanock, R M; Murphy, B R.

Affiliation

Hsu KH; Wyeth-Ayerst Research, Philadelphia, PA 19101, USA.

Vaccine ; 13(5): 509-15, 1995 Apr.

Article in En | MEDLINE | ID: mdl-7543716

Subject(s)

Mutagenesis; Respiratory Syncytial Virus, Human/genetics; Respiratory Syncytial Virus, Human/immunology; Vaccines, Attenuated/genetics; Vaccines, Attenuated/isolation & purification; Viral Vaccines/genetics; Viral Vaccines/isolation & purification; Animals; Azacitidine/pharmacology; Carcinoma, Squamous Cell/virology; Chlorocebus aethiops; Female; Fluorouracil/pharmacology; Male; Mice; Mice, Inbred BALB C; Pan troglodytes; Phenotype; Respiratory Syncytial Virus Infections/immunology; Respiratory Syncytial Virus Infections/prevention & control; Temperature; Tumor Cells, Cultured; Vero Cells; Virus Replication/physiology

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Vaccines, Attenuated / Viral Vaccines / Mutagenesis / Respiratory Syncytial Virus, Human Limits: Animals Language: En Journal: Vaccine Year: 1995 Document type: Article Affiliation country: United States Country of publication: Netherlands

Search on Google

Add to My VHL

XML

PubMed Links