IL-4 induces germ-line IgE heavy chain gene transcription in human fetal pre-B cells. Evidence for differential expression of functional IL-4 and IL-13 receptors during B cell ontogeny.

Punnonen, J; Cocks, B G; de Vries, J E

Punnonen, J; Cocks, B G; de Vries, J E.

Affiliation

Punnonen J; DNAX Research Institute of Molecular and Cellular Biology, Human Immunology Department, Palo Alto, CA 94304, USA.

J Immunol ; 155(9): 4248-54, 1995 Nov 01.

Article in En | MEDLINE | ID: mdl-7594582

Subject(s)

Antigens, CD/genetics; B-Lymphocytes/metabolism; Genes, Immunoglobulin; Immunoglobulin E/biosynthesis; Immunoglobulin Heavy Chains/genetics; Interleukin-13/genetics; Interleukin-4/genetics; Receptors, Interleukin/biosynthesis; Receptors, Interleukin/genetics; Antigens, CD/physiology; B-Lymphocytes/cytology; Base Sequence; Bone Marrow Cells; Cell Differentiation/genetics; Cell Differentiation/immunology; Fetus; Humans; Immunoglobulin E/genetics; Interleukin-13/immunology; Interleukin-13 Receptor alpha1 Subunit; Interleukin-4/immunology; Molecular Sequence Data; Receptors, Interleukin/physiology; Receptors, Interleukin-13; Receptors, Interleukin-4; Spleen/cytology; Transcription, Genetic/immunology

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Collection: 01-internacional Database: MEDLINE Main subject: Immunoglobulin E / Genes, Immunoglobulin / B-Lymphocytes / Antigens, CD / Interleukin-4 / Immunoglobulin Heavy Chains / Receptors, Interleukin / Interleukin-13 Limits: Humans Language: En Journal: J Immunol Year: 1995 Document type: Article Affiliation country: United States Country of publication: United States

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