Fluorescent substances and high molecular weight protein aggregates formed in rat heart mitochondria upon doxorubicin-induced lipid peroxidation.

Fukuda, F; Kitada, M; Horie, T; Awazu, S

Fukuda, F; Kitada, M; Horie, T; Awazu, S.

Affiliation

Fukuda F; Department of Biopharmaceutics, Tokyo College of Pharmacy, Japan.

J Pharm Pharmacol ; 47(3): 246-9, 1995 Mar.

Article in En | MEDLINE | ID: mdl-7602490

Subject(s)

Doxorubicin/toxicity; Lipid Peroxidation/drug effects; Mitochondria, Heart/drug effects; Proteins/metabolism; Animals; Binding Sites; Chlorides; Electrophoresis, Polyacrylamide Gel; Ferric Compounds/pharmacology; Fluorescence; In Vitro Techniques; Male; Mitochondria, Heart/metabolism; Molecular Weight; NAD/pharmacology; Protein Binding; Proteins/chemistry; Proteins/isolation & purification; Rats; Rats, Wistar; Reference Standards; Spectrometry, Fluorescence; Thiobarbituric Acid Reactive Substances/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Lipid Peroxidation / Proteins / Doxorubicin / Mitochondria, Heart Limits: Animals Language: En Journal: J Pharm Pharmacol Year: 1995 Document type: Article Affiliation country: Japan Country of publication: United kingdom

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