Alzheimer neurofibrillary tangles contain 2.1 nm filaments structurally identical to the microtubule-associated protein tau: a high-resolution transmission electron microscope study of tangles and senile plaque core amyloid.

Ruben, G C; Iqbal, K; Wisniewski, H M; Johnson, J E; Grundke-Iqbal, I

Ruben, G C; Iqbal, K; Wisniewski, H M; Johnson, J E; Grundke-Iqbal, I.

Affiliation

Ruben GC; Department of Biological Sciences, Dartmouth College, Hanover, NH 03755.

Brain Res ; 602(2): 164-79, 1993 Feb 05.

Article in En | MEDLINE | ID: mdl-7680597

Subject(s)

Alzheimer Disease/pathology; Amyloid/ultrastructure; Intermediate Filaments/ultrastructure; Neurofibrillary Tangles/ultrastructure; tau Proteins/ultrastructure; Alzheimer Disease/metabolism; Amyloid/metabolism; Brain/pathology; Electrophoresis, Polyacrylamide Gel; Freeze Drying; Humans; Microscopy, Electron; Neurofibrillary Tangles/metabolism; Staining and Labeling; tau Proteins/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Intermediate Filaments / Neurofibrillary Tangles / Tau Proteins / Alzheimer Disease / Amyloid Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Brain Res Year: 1993 Document type: Article Country of publication: Netherlands

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