Acute mixed-lineage leukemia t(4;11)(q21;q23) generates an MLL-AF4 fusion product.

Domer, P H; Fakharzadeh, S S; Chen, C S; Jockel, J; Johansen, L; Silverman, G A; Kersey, J H; Korsmeyer, S J

Domer, P H; Fakharzadeh, S S; Chen, C S; Jockel, J; Johansen, L; Silverman, G A; Kersey, J H; Korsmeyer, S J.

Affiliation

Domer PH; Howard Hughes Medical Institute, Washington University School of Medicine, St. Louis, MO 63110.

Proc Natl Acad Sci U S A ; 90(16): 7884-8, 1993 Aug 15.

Article in En | MEDLINE | ID: mdl-7689231

Subject(s)

Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 4; Leukemia/genetics; Recombinant Fusion Proteins/biosynthesis; Translocation, Genetic; Amino Acid Sequence; Base Sequence; Binding Sites; Chromosome Mapping; Chromosomes, Fungal; Cloning, Molecular; DNA Topoisomerases, Type II/metabolism; Humans; Molecular Sequence Data; Oligodeoxyribonucleotides; Poly A/isolation & purification; Poly A/metabolism; RNA/isolation & purification; RNA/metabolism; RNA, Messenger; Repetitive Sequences, Nucleic Acid; Restriction Mapping; Saccharomyces cerevisiae/genetics; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Tumor Cells, Cultured

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Translocation, Genetic / Chromosomes, Human, Pair 4 / Chromosomes, Human, Pair 11 / Recombinant Fusion Proteins / Leukemia Type of study: Prognostic_studies Limits: Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 1993 Document type: Article Country of publication: United States

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