Metabolism and disposition of 14C-granisetron in rat, dog and man after intravenous and oral dosing.

Clarke, S E; Austin, N E; Bloomer, J C; Haddock, R E; Higham, F C; Hollis, F J; Nash, M; Shardlow, P C; Tasker, T C; Woods, F R

Clarke, S E; Austin, N E; Bloomer, J C; Haddock, R E; Higham, F C; Hollis, F J; Nash, M; Shardlow, P C; Tasker, T C; Woods, F R.

Affiliation

Clarke SE; Department of Drug Metabolism and Pharmacokinetics, Boots Pharmaceuticals, Nottingham, UK.

Xenobiotica ; 24(11): 1119-31, 1994 Nov.

Article in En | MEDLINE | ID: mdl-7701853

Subject(s)

Granisetron/administration & dosage; Granisetron/metabolism; Administration, Oral; Adult; Animals; Bile/chemistry; Bile/drug effects; Bile/metabolism; Carbon Radioisotopes; Dogs; Female; Granisetron/analysis; Humans; Injections, Intravenous; Male; Middle Aged; Rats; Rats, Sprague-Dawley; Urine/chemistry

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Collection: 01-internacional Database: MEDLINE Main subject: Granisetron Limits: Adult / Animals / Female / Humans / Male / Middle aged Language: En Journal: Xenobiotica Year: 1994 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom

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