Sequence analysis of the 308 degrees to 311 degrees segment of the Bacillus subtilis 168 chromosome, a region devoted to cell wall metabolism, containing non-coding grey holes which reveal chromosomal rearrangements.
Microbiology (Reading)
; 141 ( Pt 2): 329-35, 1995 Feb.
Article
in En
| MEDLINE
| ID: mdl-7704262
ABSTRACT
The 29.71 kb chromosomal region of Bacillus subtilis 168 extending from 308 degrees to 311 degrees contains 18 ORFs. Functions of most of these ORFs were identified and associated with cell wall metabolism. Sequences of two non-coding regions of 0.7 and 2.2 kb flanking the ggaAB operon involved in the synthesis of poly(3-O-beta-D-glucopyranosyl N-acetylgalactosamine 1-phosphate), a minor teichoic acid, correspond to five degenerate segments of neighbouring protein-coding regions. We discuss the possibility that such grey holes are indicative of a chromosomal rearrangement which could have arisen from horizontal gene transfer.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Bacillus subtilis
/
DNA, Bacterial
/
Gene Rearrangement
/
Cell Wall
/
Chromosomes, Bacterial
Language:
En
Journal:
Microbiology (Reading)
Journal subject:
MICROBIOLOGIA
Year:
1995
Document type:
Article
Affiliation country:
Switzerland