Contrasting effects of alpha and beta globin regulatory elements on chromatin structure may be related to their different chromosomal environments.

Craddock, C F; Vyas, P; Sharpe, J A; Ayyub, H; Wood, W G; Higgs, D R

Craddock, C F; Vyas, P; Sharpe, J A; Ayyub, H; Wood, W G; Higgs, D R.

Affiliation

Craddock CF; MRC Molecular Haematology Unit, John Radcliffe Hospital, Headington, Oxford, UK.

EMBO J ; 14(8): 1718-26, 1995 Apr 18.

Article in En | MEDLINE | ID: mdl-7737123

Subject(s)

Chromatin/genetics; Chromosomes, Human, Pair 16/genetics; Gene Expression Regulation; Globins/genetics; Regulatory Sequences, Nucleic Acid/genetics; Animals; Base Sequence; Chromatin/ultrastructure; Chromosomes, Human, Pair 16/ultrastructure; DNA/metabolism; Deoxyribonuclease I/metabolism; Globins/biosynthesis; Humans; Hybrid Cells; Mice; Mice, Transgenic; Molecular Sequence Data; Multigene Family/genetics; Promoter Regions, Genetic/genetics; Sequence Deletion

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromosomes, Human, Pair 16 / Globins / Chromatin / Regulatory Sequences, Nucleic Acid / Gene Expression Regulation Limits: Animals / Humans Language: En Journal: EMBO J Year: 1995 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom

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