Relationship between the pharmacokinetics of irinotecan and diarrhea during combination chemotherapy with cisplatin.

Kudoh, S; Fukuoka, M; Masuda, N; Yoshikawa, A; Kusunoki, Y; Matsui, K; Negoro, S; Takifuji, N; Nakagawa, K; Hirashima, T

Kudoh, S; Fukuoka, M; Masuda, N; Yoshikawa, A; Kusunoki, Y; Matsui, K; Negoro, S; Takifuji, N; Nakagawa, K; Hirashima, T.

Affiliation

Kudoh S; Department of Internal Medicine, Osaka Prefectural Habikino Hospital.

Jpn J Cancer Res ; 86(4): 406-13, 1995 Apr.

Article in En | MEDLINE | ID: mdl-7775263

Subject(s)

Antineoplastic Agents, Phytogenic/adverse effects; Antineoplastic Agents, Phytogenic/pharmacokinetics; Antineoplastic Combined Chemotherapy Protocols/adverse effects; Antineoplastic Combined Chemotherapy Protocols/pharmacokinetics; Camptothecin/analogs & derivatives; Diarrhea/chemically induced; Diarrhea/metabolism; Adult; Aged; Antineoplastic Agents, Phytogenic/administration & dosage; Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Camptothecin/administration & dosage; Camptothecin/adverse effects; Camptothecin/pharmacokinetics; Carcinoma, Non-Small-Cell Lung/drug therapy; Carcinoma, Non-Small-Cell Lung/metabolism; Carcinoma, Small Cell/drug therapy; Carcinoma, Small Cell/metabolism; Cisplatin/administration & dosage; Drug Interactions; Female; Humans; Irinotecan; Lung Neoplasms/drug therapy; Lung Neoplasms/metabolism; Male; Middle Aged; Topoisomerase I Inhibitors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Camptothecin / Antineoplastic Combined Chemotherapy Protocols / Diarrhea / Antineoplastic Agents, Phytogenic Type of study: Clinical_trials / Prognostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Jpn J Cancer Res Journal subject: NEOPLASIAS Year: 1995 Document type: Article Country of publication: Japan

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