Establishment and characterization of a new Ph1-positive chronic myeloid leukemia cell line MC3 with trilineage phenotype and an altered p53 gene.

Okabe, M; Kunieda, Y; Nakane, S; Kurosawa, M; Itaya, T; Vogler, W R; Shoji, M; Miyazaki, T

Okabe, M; Kunieda, Y; Nakane, S; Kurosawa, M; Itaya, T; Vogler, W R; Shoji, M; Miyazaki, T.

Affiliation

Okabe M; Third Department of Internal Medicine, Hokkaido University School of Medicine, Sapporo, Japan.

Leuk Lymphoma ; 16(5-6): 493-503, 1995 Feb.

Article in En | MEDLINE | ID: mdl-7787756

Subject(s)

Blast Crisis/pathology; Genes, p53; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/pathology; Tumor Cells, Cultured; 3T3 Cells; Animals; Base Sequence; Biomarkers; Blast Crisis/genetics; Cell Division/drug effects; Culture Media, Serum-Free; DNA, Neoplasm/genetics; Fatal Outcome; Female; Fusion Proteins, bcr-abl/analysis; Genes, abl; Genes, ras; Humans; Immunophenotyping; Interleukin-1/pharmacology; Interleukin-3/pharmacology; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/genetics; Mice; Middle Aged; Molecular Sequence Data; Neoplasm Proteins/analysis; Neoplastic Stem Cells/chemistry; Neoplastic Stem Cells/drug effects; Point Mutation; Polymerase Chain Reaction; Recombinant Proteins/pharmacology; Transfection; Tumor Cells, Cultured/drug effects

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Tumor Cells, Cultured / Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Blast Crisis / Genes, p53 Limits: Animals / Female / Humans / Middle aged Language: En Journal: Leuk Lymphoma Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 1995 Document type: Article Affiliation country: Japan Country of publication: United States

Search on Google

Add to My VHL

XML

PubMed Links