Chromosomal localization of a gene, GF1, encoding a novel zinc finger protein reveals a new syntenic region between man and rodents.

Bell, D W; Taguchi, T; Jenkins, N A; Gilbert, D J; Copeland, N G; Gilks, C B; Zweidler-McKay, P; Grimes, H L; Tsichlis, P N; Testa, J R

Bell, D W; Taguchi, T; Jenkins, N A; Gilbert, D J; Copeland, N G; Gilks, C B; Zweidler-McKay, P; Grimes, H L; Tsichlis, P N; Testa, J R.

Affiliation

Bell DW; Department of Medical Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.

Cytogenet Cell Genet ; 70(3-4): 263-7, 1995.

Article in En | MEDLINE | ID: mdl-7789186

ABSTRACT

The Gfi1 gene encodes a zinc finger protein which binds DNA and is involved in transcriptional regulation. Gfi1 was assigned to the central portion of mouse Chr 5 by interspecific backcross mapping and to human chromosome band 1p22 and rat chromosome band 14p22 by fluorescence in situ hybridization (FISH). Comparative mapping data presented here describes a new syntenic region between man and rodents.

Subject(s)

Chromosome Mapping; Chromosomes, Human, Pair 1; DNA-Binding Proteins/genetics; Hominidae/genetics; Mice/genetics; Rats/genetics; Transcription Factors; Zinc Fingers/genetics; Animals; Chromosome Banding; Cricetinae; Crosses, Genetic; Female; Humans; Hybrid Cells; In Situ Hybridization, Fluorescence; Male; Mice, Inbred C57BL; Muridae/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Rats / Transcription Factors / Chromosomes, Human, Pair 1 / Hominidae / Zinc Fingers / Chromosome Mapping / DNA-Binding Proteins / Mice Limits: Animals / Female / Humans / Male Language: En Journal: Cytogenet Cell Genet Year: 1995 Document type: Article Affiliation country: United States Country of publication: Switzerland

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