[Paraplegia associated with HTLV 1 in Martinique. Study of 271 cases including 70 with neuromuscular involvement]. / Paraplégie associée à l'HTLV1 en Martinique. Etude de 271 cas dont 70 avec atteinte neuromusculaire.
Bull Soc Pathol Exot
; 86(5 Pt 2): 433-8, 1993.
Article
in Fr
| MEDLINE
| ID: mdl-7819796
ABSTRACT
To date, 271 cases of HTLV1-associated paraplegia have been observed in Martinique (French West Indies). The clinical picture consisted mostly in a spastic paraparesis or paraplegia with sphincter disturbances (80%) and lower limbs pains (60%). The severity of the disease appeared variable after a mean disease duration of 6.5 years, 40% of the patients could walk without help, 35% used a single crutch, and 25% used a couple of crutches or were confined to a wheelchair. A variable neuromuscular component was observed in 70 cases (25.4%). In 38 cases, the peripheral signs (SIGNS) or the myositis were only mild. In contrast, 25 patients presented with severe amyotrophy evoking amyotrophic lateral sclerosis, and 7 other had features of dermatopolymyositis. Lastly, an extra-neural spreading of the disease was extremely frequent, including lymphocytic alveolitis (76%), sicca syndrome (69%) and more rarely uveitis, arthritis or vasculitis.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Human T-lymphotropic virus 1
/
Paraparesis, Tropical Spastic
Type of study:
Risk_factors_studies
Limits:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Child
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
Caribe
/
Martinica
Language:
Fr
Journal:
Bull Soc Pathol Exot
Year:
1993
Document type:
Article