The measurement of skin blood flow in peripheral vascular disease by epicutaneous application of Xenon133.
J Bone Joint Surg Am
; 58(6): 833-7, 1976 Sep.
Article
in En
| MEDLINE
| ID: mdl-783163
ABSTRACT
Radioactive xenon133 applied epicutaneously was used to study the skin blood flow below the knee in sixteen normal subjects, in eight patients with peripheral vascular disease not requiring amputation, and in a blind study of twenty-nine patients requiring amputation. Following these twenty-nine amputations, the flow rates were made known and correlated with the rates of healing. When the flow rates were above 1.5 milliliters per minute per 100 grams of tissue (skin), the wounds generally healed. In thirteen other patients, Syme or below-the-knee amputations were performed on the basis of the flow rates, and all of the wounds healed. The test, therefore, is now used routinely prior to amputation for peripheral vascular disease as an adjunct to clinical judgment in the determination of the level of amputation.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Skin
/
Xenon Radioisotopes
/
Ischemia
/
Leg
Aspects:
Patient_preference
Limits:
Adult
/
Humans
Language:
En
Journal:
J Bone Joint Surg Am
Year:
1976
Document type:
Article