[Cardiac retransplantation: is it justified in childhood?]. / Ritrapianto cardiaco: è giustificato in età pediatrica?
G Ital Cardiol
; 24(12): 1575-80, 1994 Dec.
Article
in It
| MEDLINE
| ID: mdl-7883130
ABSTRACT
A 7-year-old boy had undergone heart transplantation (HT) at 1 year of age. The immunosuppressive regimen consisted of cyclosporine and azathioprine (Cy+Aza). During the follow-up there were 7 episodes of moderate rejection 4 of them occurred during the first 3 months. He had cytomegalovirus (CMV) seroconversion 4 years after HT. After 5 years since he underwent primary HT, cardiac catheterization and selective coronary angiography, performed on a yearly basis, showed triple vessel occlusive disease. The treadmill test was positive. During the following year, the patient's clinical condition deteriorated in May '92 he underwent retransplantation. Cross-match was negative and there were no common HLA-DR antigens between the first and the second donor heart. Only 1 rejection episode occurred during the first 18 months of follow-up. Despite the shortage of donor hearts we feel that retransplantation is justified as an elective procedure in pediatric patients with cardiac allograft vasculopathy (CAV).
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Heart Transplantation
Type of study:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
Limits:
Child
/
Humans
/
Male
Language:
It
Journal:
G Ital Cardiol
Year:
1994
Document type:
Article