Model systems for oxidative drug metabolism studies. Catalytic behavior of water-soluble metalloporphyrins depends on both the intrinsic robustness of the catalyst and the nature of substrates.

Vidal, M; Bonnafous, M; Defrance, S; Loiseau, P; Bernadou, J; Meunier, B

Vidal, M; Bonnafous, M; Defrance, S; Loiseau, P; Bernadou, J; Meunier, B.

Affiliation

Vidal M; Laboratoire de Chimie Thérapeutique, Faculté de Pharmacie, Toulouse, France.

Drug Metab Dispos ; 21(5): 811-7, 1993.

Article in En | MEDLINE | ID: mdl-7902241

Subject(s)

Metalloporphyrins/pharmacology; Models, Biological; Pharmaceutical Preparations/metabolism; Acetaminophen/analogs & derivatives; Acetaminophen/metabolism; Ellipticines/metabolism; Ferric Compounds/pharmacology; Horseradish Peroxidase/metabolism; Kinetics; Manganese/pharmacology; Molecular Conformation; Oxidation-Reduction; Porphyrins/pharmacology; Solubility; Spectrophotometry; Structure-Activity Relationship; Water

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Pharmaceutical Preparations / Metalloporphyrins / Models, Biological Language: En Journal: Drug Metab Dispos Journal subject: FARMACOLOGIA Year: 1993 Document type: Article Affiliation country: France Country of publication: United States

Search on Google

Add to My VHL

XML

PubMed Links