Two multidrug-resistant Friend leukemic cell lines selected with different drugs exhibit overproduction of different P-glycoproteins.

Savaraj, N; Lampidis, T J; Zhao, J Y; Wu, C J; Teeter, L D; Kuo, M T

Savaraj, N; Lampidis, T J; Zhao, J Y; Wu, C J; Teeter, L D; Kuo, M T.

Affiliation

Savaraj N; Department of Oncology, University of Miami, Florida 33101.

Cancer Invest ; 12(2): 138-44, 1994.

Article in En | MEDLINE | ID: mdl-7907527

Subject(s)

Antimetabolites, Antineoplastic/metabolism; Carrier Proteins/metabolism; Doxorubicin/metabolism; Friend murine leukemia virus; Leukemia, Experimental/metabolism; Membrane Glycoproteins/metabolism; Retroviridae Infections/metabolism; Rhodamines/metabolism; Tumor Virus Infections/metabolism; Verapamil/metabolism; ATP Binding Cassette Transporter, Subfamily B, Member 1; Doxorubicin/pharmacology; Drug Resistance/genetics; Gene Expression Regulation, Leukemic; Leukemia, Experimental/genetics; RNA, Messenger/metabolism; RNA, Neoplasm/metabolism; Retroviridae Infections/genetics; Rhodamine 123; Tumor Cells, Cultured; Tumor Virus Infections/genetics; Verapamil/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Rhodamines / Tumor Virus Infections / Membrane Glycoproteins / Verapamil / Leukemia, Experimental / Carrier Proteins / Doxorubicin / Retroviridae Infections / Friend murine leukemia virus / Antimetabolites, Antineoplastic Language: En Journal: Cancer Invest Year: 1994 Document type: Article Country of publication: United kingdom

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