The synthesis of trans-3,4-bis-(3,4-dihydroxyphenyl)pyrrolidine, a novel DA1 agonist.
Chem Pharm Bull (Tokyo)
; 41(3): 633-5, 1993 Mar.
Article
in En
| MEDLINE
| ID: mdl-8097437
The synthesis of trans-3,4-bis-(3,4-dihydroxyphenyl)pyrrolidine by the Michael reaction of esterenolate with nitro olefin is described. This compound was expected to be the agonist toward dopamine (DA1) receptor with equipotent affinity and to be more selective than dopamine itself.
Search on Google
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pyrrolidines
/
Dopamine Agents
/
Catechols
/
Receptors, Dopamine D1
/
Hemodynamics
Limits:
Animals
Language:
En
Journal:
Chem Pharm Bull (Tokyo)
Year:
1993
Document type:
Article
Affiliation country:
Japan
Country of publication:
Japan